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KMID : 1036520120020020099
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Clinical Neuro-Ophthalmology
2012 Volume.2 No. 2 p.99 ~ p.102
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Do the Paramedian Tract Neurons in Pons Take a Role as a Vertical Neural Integrator in Humans?
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Lee Hyung
Kim Hyun-Ah
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Abstract
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Impairment of gaze holding mechanism and gaze-evoked nystagmus (GEN) in the vertical plane due to a focal brain lesion is usually caused by a failure of the vertical neural integrator, which is known to be localized in the interstitial nucleus of the Cajal in the upper midbrain. We report a patient with hemorrhagic stroke involving the paramedian pontine tegmentum who presented with vertical GEN due to a failure of vertical gaze holding mechanism and unilateral internuclear ophthalmoplegia. The possible structure taking a role as a vertical neural integrator in this patient might be the paramedian tract (PMT) neuron.
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KEYWORD
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Gaze-evoked nystagmus, Neural integrator, Paramedian tract neurons
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